DTI Bca DNA Polymerase- Glycerol Free originates from a thermophilic bacterium Bacillus caldotenax, that lacks 5’ → 3’ exonuclease activity. By introducing mutations into the protein, the activity of both DNA polymerase and reverse transcriptase is highly enhanced while exerting the original strong strand-displacement activity. Therefore, the isothermal amplifications using this enzyme enable to amplify the target product from a little nucleic acid in a shorter time. This enzyme is originally isolated and developed independently by Takara Bio Inc, Japan. DTI manufactures and sells it under an agreement with Takara Bio Inc.
