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TaKaRa LA Taq DNA Polymerase combines Taq DNA polymerase and a DNA proofreading polymerase, with 3’→5’ exonuclease activity, to enable PCR amplification of very long DNA templates (long-range PCR). This mixture of enzymes allows for long and accurate (LA) PCR of targets from a variety of templates, including genomic DNA. LA Taq DNA polymerase is supplied with optimized LA PCR Buffer II (with or without Mg2+) and dNTPs.The presence of the proofreading polymerase increases fidelity as compared to Taqpolymerase alone. Using the LA Taq long-PCR system, routine extensions of 20 kb are possible, and products of up to 48 kb can be obtained for some templates.